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Importantly, the neuroprotective effects of both inulin and SCFAs are contingent upon the activation of the IL-10 signaling pathway [108]

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The observed decrease in MCP-1 staining intensity suggests that intranasal administration of GHK-Cu in transgenic 5xFAD mice had a reducing effect on the AD-induced inflammatory phenotype and could serve as a reliable prototype to study drugs that slow or stop progression of AD [40]