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Analysis of Central Nervous System Karyopyknotic Cells Modified Bielschowsky’s silver staining and Klüver–Barrera staining (using Klüver–Barrera Luxol fast blue) were performed to demonstrate argentophilic neurites, axonal spheroids, and neuronal cell bodies, particularly in brain karyopyknotic areas ( (file:/ The brain was dissected according to NTP-7 at Levels 3 and 6 with neuroanatomic subsites presented in certain brain sections using coronal sections with three mandatory sections (Knezevic et al., 2021a

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We also summarize the diverse forms of oligodendrocyte cell death that occur in the cuprizone model as understanding oligodendrocyte death may illuminate mechanisms of cuprizone toxicity